Observational Study of "Chai Hu Jia Long Gu Mu Li Tang" (Bupleurum adnd Dragon Bone) on Menopausal Syndrome

Teo, Elsie Sin May (2015) Observational Study of "Chai Hu Jia Long Gu Mu Li Tang" (Bupleurum adnd Dragon Bone) on Menopausal Syndrome. Other thesis, INTI International University.

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Abstract

Introduction. “Menopause” denotes the final cessation of menstruation, resulting from loss of ovarian follicular function, usually due to aging. Symptoms that have been shown to be associated with estrogen deficiency after the menopause are hot flushes and night sweats, insomnia and vaginal dryness. Vasomotor episodes with hot flushes and night sweating are the most prevalent complaints related to menopause. Hormone therapy with estrogen is considered as the most effective treatment in treating symptoms of menopause. However, recent research show that long term use of estrogen increases the risk of serious adverse effects, so, prompting sufferers to seek other therapies. Aims. The main objective for this research is to investigate the effectiveness of Chai Hu Jia Long Gu Mu Li Tang (Bupleurum and Dragon Bone) in treating menopause syndrome. The specific objectives are to study the effectiveness of herbal formula Chai Hu Jia Long Gu Mu Li Tang (Bupleurum and Dragon Bone) in treating physical and psychological health problems of woman aged between 45 to 55, and to investigate the administration of herbal formula Chai Hu Jia Long Gu Mu Li Tang (Bupleurum and Dragon Bone) would result in the participants in the study achieving lower scores on the Menopause Rating Scale compared with baseline scores reported before the administration of herbal formula. Method. A small sample, non-randomized cross sectional clinical study design was used in this study. This study was carried out in INTI International University and Negeri Sembilan Chinese Maternity Hospital (NSCMH). Patients were scheduled to receive treatment for 3 consecutive weeks. Each week, patients was given medicinal powder of Chai Hu Jia Long Gu Mu Li Tang. A Menopause Rating Scale (MRS) was the given to the patients to evaluate their conditions and to check if there is any improvement or side effect upon consuming the medication. All results were recorded and analyzed in a table. Result. After the course of treatment, the average level for each dimension was reduced, the average level of psychological symptoms was reduced up to 53.57 percent, for somatic-vegetative symptoms, it was reduced up to 53.33 percent, while for urogenital symptoms, it was reduced up to 66.76 percent. Overall, it shows an improvement for all the 3 dimensions, especially in urogenital symptoms. Conclusion. Bupleurum and Dragon Bone (Chai Hu Jia Long Gu Mu Li Ting) is effective in managing menopausal symptoms.

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