S., Vijaya Kumar and P., Sankar and R., Varatharajan (2009) Anti-inflammatory activity of roots of Achyranthes aspera. Pharmaceutical Biology, 47 (10). pp. 973-975. ISSN 1744-5116
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Abstract
This study investigated the anti-inflammatory potential of the alcohol extract of Achyranthes aspera Linn. (Amaranthaceae) in Wistar rats after oral administration (50, 100, and 200 mg/kg). This was done using the carrageenan-induced paw edema method (acute inflammatory model) and cotton pellet granuloma test (chronic inflammatory model). The alcohol extract showed significant suppressed granuloma formation. Collectively, these data demonstrate promising anti-inflammatory activity against both acute and chronic inflammation. In addition, inhibition of prostaglandins and bradykinins may play a role. This study reveal- ing the promising anti-inflammatory activity of Achyranthes aspera roots has been carried out scientifically for the first time.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Alcohol extract; Achyranthes aspera (Amaranthaceae); anti-inflammatory activity; roots |
| Subjects: | Q Science > QR Microbiology |
| Divisions: | Faculty of Medicine, Health and Life Sciences > School of Physiotherapy |
| Depositing User: | Unnamed user with email masilah.mansor@newinti.edu.my |
| Date Deposited: | 25 Apr 2016 05:36 |
| Last Modified: | 25 Apr 2016 05:36 |
| URI: | http://eprints.intimal.edu.my/id/eprint/200 |
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