Anti-inflammatory activity of roots of Achyranthes aspera

S., Vijaya Kumar and P., Sankar and R., Varatharajan (2009) Anti-inflammatory activity of roots of Achyranthes aspera. Pharmaceutical Biology, 47 (10). pp. 973-975. ISSN 1744-5116


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This study investigated the anti-inflammatory potential of the alcohol extract of Achyranthes aspera Linn. (Amaranthaceae) in Wistar rats after oral administration (50, 100, and 200 mg/kg). This was done using the carrageenan-induced paw edema method (acute inflammatory model) and cotton pellet granuloma test (chronic inflammatory model). The alcohol extract showed significant suppressed granuloma formation. Collectively, these data demonstrate promising anti-inflammatory activity against both acute and chronic inflammation. In addition, inhibition of prostaglandins and bradykinins may play a role. This study reveal- ing the promising anti-inflammatory activity of Achyranthes aspera roots has been carried out scientifically for the first time.

Item Type: Article
Uncontrolled Keywords: Alcohol extract; Achyranthes aspera (Amaranthaceae); anti-inflammatory activity; roots
Subjects: Q Science > QR Microbiology
Divisions: Faculty of Medicine, Health and Life Sciences > School of Physiotherapy
Depositing User: Unnamed user with email
Date Deposited: 25 Apr 2016 05:36
Last Modified: 25 Apr 2016 05:36

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